V. N. Solopov, I. V. Lunichkina<\/p>\n
Expectoration disturbances in patients with COPD<\/p>\n
Soviet Association of aid to patients with cystic fibrosis
\nPogodinscaya 8 — 2, 119121 Moscow, USSR.<\/p>\n
We developed a method of estimation of the evacuation time (expectoration time) (Texp) of bronchial contents stained with haemoglobin (Hb) in patients with COPD. 155 patients were examined: 44 with intrinsic asthma, 111 with chronic bronchitis. It was found that Texp depends on the type of illness (X\u00b1m): asthma 41.5\u00b14.4 h, non-obstructive 31.4\u00b14.2 h., obstructive 64.7\u00b14.3 h and pyo-obstructive bronchitis 116.1\u00b17.8 h. Expectoration efficacy during a comparison of different drugs amounted to (X\u00b1m): 1) peroral: ambroxol 41.5\u00b15.1%, bromhexine 37.9\u00b18.6%, Mucodyne 30.4\u00b17.6%; 2) inhalation: n-acetyl-cysteine 55.3\u00b15.3%, 2% solution of sodium bicarbonate 58.4\u00b13.8%, sodium bicarbonate in a dry aerosol form 52.5\u00b19.7%. Conclusion: the choice of drug and introduction manner (peroral or inhalation) must be determined by the value of the expectoration time.<\/p>\n
The European Respiratory Journal, 1990, Vol. 3, Suppl. 10, P1766.<\/p>\n
\n","protected":false},"excerpt":{"rendered":"
V. N. Solopov, I. V. Lunichkina Expectoration disturbances in patients with COPD Soviet Association of aid to patients with cystic fibrosis Pogodinscaya 8 — 2, 119121 Moscow, USSR. We developed a method of estimation of the evacuation time (expectoration time) (Texp) of bronchial contents stained … <\/p>\n